PlayN ("Cross platform game library for N>=5 platforms") allows one to provide one gaming solution across multiple front-ends. In process, making it a lot easier to bridge the different support requirements of front-end technologies by just implementing to one. The abstractions are generic enough to provide a number of different compatibilities at compile time: Java on Desktop, Android, HTML5, iOS, Flash, and provisions for a lot more. The framework is Java oriented and is built on top of GWT.
Another, alternative to PlayN is libGDX with similar multi-platform options. More options, include:
Unity 3D - designed for ease of creation
GameMaker - visual programming simplified
GameDevelop - visual game development
Unreal Development Kit - game development with advanced visualizations and simulations
Visual 3D Game Engine - rapid development of next generation 3D games
